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Center for Applied Biotechnology and Molecular Medicine

Publications 2022

* supported by a CABMM Start-up Grant
** performed partly on the CABMM Research Platform

Lädermann A, Gehrke R, Klein K, Karol A, Darwiche S, Schwarzenberg P, Steffen T, Wieser K, Kronen P, von Rechenberg B
Studying Edema Formation After Release of the Infraspinatus Tendon as an Experimental Model of Rotator Cuff Tears in Sheep: A Preliminary Imaging and Morphological Analysis
Am J Sports Med. 2022 Dec;50(14):3934-3940
PubMed

** Torres-Netto EA, Abdshahzadeh H, Abrishamchi R, Hafezi NL, Hillen M, Ambrósio R Jr, Randleman JB, Spoerl E, Gatinel D, Hafezi F
Reply: Ex Vivo Eye Rubbing Evidence
J Refract Surg. 2022 Nov;38(11):752-753
PubMed

** Abdshahzadeh H, Abrishamchi R, Aydemir ME, Hafezi N, Hillen M, Torres-Netto EA, Lu NJ, Hafezi F
Repeated application of riboflavin during corneal cross-linking does not improve the biomechanical stiffening effect ex vivo
Exp Eye Res. 2022 Nov;224:109267
PubMed

Guerrero J, Ghayor C, Bhattacharya I, Weber FE
Osteoconductivity of bone substitutes with filament-based microarchitectures: Influence of directionality, filament dimension, and distance
Int J Bioprint. 2022 Oct 27;9(1):626
PubMed

Stephenson MC, Krishna L, Pannir Selvan RM, Tai YK, Kit Wong CJ, Yin JN, Toh SJ, Torta F, Triebl A, Fröhlich J, Beyer C, Li JZ, Tan SS, Wong CK, Chinnasamy D, Pakkiri LS, Lee Drum C, Wenk MR, Totman JJ, Franco-Obregón A
Magnetic field therapy enhances muscle mitochondrial bioenergetics and attenuates systemic ceramide levels following ACL reconstruction: Southeast Asian randomized-controlled pilot trial
J Orthop Translat. 2022 Oct 13;35:99-112
ScienceDirect

** Hafezi F, Lu NJ, Assaf JF, Hafezi NL, Koppen C, Vinciguerra R, Vinciguerra P, Hillen M, Awwad ST
Demarcation Line Depth in Epithelium-Off Corneal Cross-Linking Performed at the Slit Lamp
J Clin Med. 2022 Oct 4;11(19):5873
PubMed

** Hafezi F
Corneal Cross-Linking: Epi-On
Cornea. 2022 Oct 1;41(10):1203-1204 [Epub ahead of print]
PubMed

** Lu NJ, Hafezi F, Rozema JJ, Hillen M, Hafezi N, Zhang J, Koppen C
Repeatability of a Scheimpflug tonometer to measure biomechanical parameters before and after myopic refractive surgery
J Cataract Refract Surg. 2022 Sep 1;48(9):1057-1062
PubMed

** Achiron A, Elhaddad O, Regev T, Krakauer Y, Tsumi E, Hafezi F, Knyazer B
PACK Cross-Linking as Adjuvant Therapy Improves Clinical Outcomes in Culture-Confirmed Bacterial Keratitis
Cornea. 2022 Sep 1;41(9):1069-1073
PubMed

** Torres-Netto EA, Abdshahzadeh H, Abrishamchi R, Hafezi NL, Hillen M, Ambrósio R Jr, Randleman JB, Spoerl E, Gatinel D, Hafezi F
The Impact of Repetitive and Prolonged Eye Rubbing on Corneal Biomechanics
J Refract Surg. 2022 Sep;38(9):610-616
PubMed

Kuratli J, Leonard CA, Frohns A, Schoborg R, Piazena H, Borel N
Refinement of water-filtered infrared A (wIRA) irradiations of in vitro acute and persistent chlamydial infections.
J Photochem Photobiol B. 2022 Sep;234:112533
PubMed

** Mazzotta C, Balamoun AA, Chabib A, Rechichi M, D`Oria F, Hafezi F, Bagaglia SA, Ferrise M
Transepithelial Enhanced Fluence Pulsed Light M Accelerated Crosslinking for Early Progressive Keratoconus with Chemically Enhanced Riboflavin Solutions and Air Room Oxygen.
J Clin Med. 2022 Aug 27;11(17):5039
PubMed

* Bakirci E, Guenat OT, Ahmad SS, Gantenbein B
Tissue engineering approaches for the repair and regeneration of the anterior cruciate ligament: towards 3D bioprinted ACL-on-chip.
Eur Cell Mater. 2022 Aug 8;44:21-42
PubMed

** Hafezi F, Munzinger A, Goldblum D, Hillen M, Tandogan T
Repeated High-Fluence Accelerated Slitlamp-Based Photoactivated Chromophore for Keratitis Corneal Cross-Linking for Treatment-Resistant Fungal Keratitis.
Cornea. 2022 Aug 1;41(8):1058-1061
PubMed

Schweizer TA, Andreoni F, Acevedo C, Scheier TC, Heggli I, Maggio EM, Eberhard N, Brugger SD, Dudli S, Zinkernagel AS
Intervertebral disc cell chondroptosis elicits neutrophil response in Staphylococcus aureus spondylodiscitis.
Front Immunol. 2022 Jul 28;13:908211
PubMed

Hafezi F, Hillen M, Kollros L, Tan J, Awwad ST
A New Postoperative Regimen after CXL and PRK Using Topical NSAID and Steroids on the Open Ocular Surface.
J Clin Med. 2022 Jul 15;11(14):4109
PubMed

** Torres-Netto EA, Hafezi F, Kling S
Intracorneal Ring Segment Implantation Results in Corneal Mechanical Strengthening Visualized With Optical Coherence Elastography.
J Refract Surg. 2022 Jul;38(7):459-464
PubMed

** Lu NJ, Elsheikh A, Rozema JJ, Hafezi N, Aslanides IM, Hillen M, Eckert D, Funck C, Koppen C, Cui LL, Hafezi F
Combining Spectral-Domain OCT and Air-Puff Tonometry Analysis to Diagnose Keratoconus.
J Refract Surg. 2022 Jun;38(6):374-380
PubMed

** Hashemi H, Roberts CJ, Ambrósio R Jr, Mehravaran S, Hafezi F, Vinciguerra R, Vinciguerra P, Panahi P, Asgari S
Comparative Contralateral Randomized Clinical Trial of Standard (3 mW/cm2) Versus Accelerated (9 mW/cm2) CXL in Patients With Down Syndrome: 3-Year Results.
J Refract Surg. 2022 Jun;38(6):381-388
PubMed

Ren T, Klein K, von Rechenberg B, Darwiche S, Dailey HL
Image-based radiodensity profilometry measures early remodeling at the bone-callus interface in sheep.
Biomech Model Mechanobiol. 2022 Apr;21(2):615-626
PubMed

Philippe V, Laurent A, Hirt-Burri N, Abdel-Sayed P, Scaletta C, Schneebeli V, Michetti M, Brunet JF, Applegate LA, Martin R
Retrospective Analysis of Autologous Chondrocyte-Based Cytotherapy Production for Clinical Use: GMP Process-Based Manufacturing Optimization in a Swiss University Hospital.
Cells. 2022 Mar 17;11(6):1016
PubMed

Feusi O, Karol A, Fleischmann T, von Rechenberg B, Bouaicha S, Werner CML, Jentzsch T
Platelet-rich plasma as a potential prophylactic measure against frozen shoulder in an in vivo shoulder cantracture model.
Arch Orthop Trauma Surg. 2022 Mar;142(3):363-372
PubMed

* Rodríguez JMM, Fonfara S, Hetzel U, Kipar A
Feline hypertrophic cardiomyopathy: reduced microvascular density and involvement of CD34+ interstitial cells
Vet Pathol. 2022 Mar;59(2):269-283
PubMed

** Torres-Netto EA, Kling S
Corneal Strain Induced by Intracorneal Ring Segment Implantation Visualized With Optical Coherence Elastography
J Refract Surg. 2022 Mar;38(3):210-216
PubMed

* Herger N, Bermudez-Lekerika P, Farshad M, Albers CE, Distler O, Gantenbein B, Dudli S
Should Degenerated Intervertebral Discs of Patients with Modic Type 1 Changes Be Treated with Mesenchymal Stem Cells?
Int J Mol Sci. 2022 Feb 28;23(5):2721
PubMed

Inglis B, Schwarzenberg P, Klein K, von Rechenberg B, Darwiche S, Dailey HL
Biomechanical duality of fracture healing captured using virtual mechanical testing and validated in ovine bones
Sci Rep. 2022 Feb 15;12(1):2492
PubMed

Ghayor C, Bhattacharya I, Guerrero J, Özcan M, Weber FE
3D-Printed HA-Based Scaffolds for Bone Regeneration: Microporosity, Osteoconduction and Osteoclastic Resorption
Materials (Basel). 2022 Feb 15;15(4):1433
PubMed

** Burkard T, Holmberg D, Thorell A, Hafezi F, Burden AM
The association between bariatric surgery and cataract: a propensity score-matched cohort study
Surg Obes Relat Dis. 2022 Feb;18(2):217-224
PubMed

* Mainardi A, Cambria E, Occhetta P, Martin I, Barbero A, Schären S, Mehrkens A, Krupkova O
Intervertebral Disc-on-a-Chip as Advanced In Vitro Model for Mechanobiology Research and Drug Testing: A Review and Perspective
Front Bioeng Biotechnol. 2022 Jan 28;9:826867
PubMed

Tai YK, Chan KKW, Fong CHH, Ramanan S, Yap JLY, Yin JN, Yip YS, Tan WR, Koh APF, Tan NS, Chan CW, Huang RYJ, Li JZ, Fröhlich J, Franco-Obregón A
Modulated TRPC1 Expression Predicts Sensitivity of Breast Cancer to Doxorubicin and Magnetic Field Therapy: Segue Towards a Precision Medicine Approach
Front Oncol. 2022 Jan 24;11:783803
PubMed

** Hafezi F, Hosny M, Shetty R, Knyazer B, Chen S, Wang Q, Hashemi H, Torres-Netto EA; PACK-CXL Working Group
PACK-CXL vs. antimicrobial therapy for bacterial, fungal, and mixed infectious keratitis: a prospective randomized phase 3 trial.
Eye Vis (Lond). 2022 Jan 7;9(1):2
PubMed

** Frese L, Darwiche SE, Gunning ME, Hoerstrup SP, von Rechenberg B, Giovanoli P, Calcagni M
Optimizing large-scale autologous human keratinocyte sheets for major burns - Toward an animal-free production and a more accessible clinical application
Health Sci Rep. 2022 Jan 7;5(1):e449
PubMed

** Hafezi F, Kling S, Gilardoni F, Hafezi N, Hillen M, Abrishamchi R, Gomes JAP, Mazzotta C, Randleman JB, Torres-Netto EA
Reply to comment on: Individualized Corneal Cross-linking With Riboflavin and UV-A in Ultrathin Corneas: The Sub400 Protocol.
Am J Ophthalmol. 2022 Jan;233:243-245
PubMed

* Generali M, Kehl D, Wanner D, Okoniewski MJ, Hoerstrup SP, Cinelli P
Heterogenous expression of ACE2 and TMPRRS2 in mesenchymal stromal cells
J Cell Mol Med. 2022 Jan;26(1):228-234
PubMed

** Hafezi F, Hillen M, Kollros L, Hafezi NL, Torres-Netto EA
Corneal Cross-linking in Thin Corneas: From Origins to State of the Art
touchREVIEWS in Ophthalmology. 2022;16(1):13-6
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