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Center for Applied Biotechnology and Molecular Medicine

Publications 2020

* supported by a CABMM Start-up Grant
** performed partly on the CABMM Research Platform

Ghayor C, Chen TH, Bhattacharya I, Özcan M, Weber FE
Microporosities in 3D-Printed Tricalcium-Phosphate-Based Bone Substitutes Enhance Osteoconduction and Affect Osteoclastic Resorption.
Int J Mol Sci. 2020 Dec 4;21(23):9270
PubMed

Plecko M, Klein K, Planzer K, Wähnert D, Behm P, Ferguson SJ, Brianza S, Stadelmann VA, von Rechenberg B
Variable fixation promotes callus formation: an experimental study on transverse tibial osteotomies stabilized with locking plates.
BMC Musculoskelet Disord. 2020 Dec 3;21(1):806
PubMed

Kuratli J, Leonard CA, Nufer L, Marti H, Schoborg R, Borel N
Maraviroc, celastrol and azelastine alter Chlamydia trachomatis development in HeLa cells.
J Med Microbiol. 2020 Dec;69(12):1351-1366
PubMed

** Belin MW, Alizadeh R, Torres-Netto EA, Hafezi F, Ambrósio R Jr, Pajic B
Determining Progression in Ectatic Corneal Disease.
Asia Pac J Ophthalmol (Phila). 2020 Dec;9(6):541-548
PubMed

* Mallone A, Gericke C, Hosseini V, Vogel V, Chahbi K, Walther JH, Haenseler W, von Eckardstein A, Emmert MY, Weber B, Hoerstrup SP
Human induced pluripotent stem cell-derived arteries as personalized models of atherosclerosis on-a-chip.
bioRxiv. 2020 Nov 27 [preprint]
bioRxiv

* Schmidli MR, Sadowska A, Cvitas I, Gantenbein B, Lischer HEL, Forterre S, Hitzl W, Forterre F, Wuertz-Kozak K
Fibronectin Fragments and Inflammation During Canine Intervertebral Disc Disease.
Front Vet Sci. 2020 Nov 16;7:547644
PubMed

Khera N, Ghayor C, Lindholm AK, Pavlova E, Atanassova N, Weber FE
Reversible Contraceptive Potential of FDA Approved Excipient N,N-Dimethylacetamide in Male Rats.
Front Physiol. 2020 Nov 10;11:601084
PubMed

** Zhang H, Roozbahani M, Piccinini AL, Hafezi F, Scarcelli G, Randleman JB
Brillouin microscopic depth-dependent analysis of corneal crosslinking performed over or under the LASIK flap.
J Cataract Refract Surg. 2020 Nov;46(11):1543-1547
PubMed

* Capossela S, Mathew V, Boos M, Bertolo A, Krupkova O, Stoyanov JV
Novel Fast and Reliable Method for Nano-Erythrosome Production Using Shear Force.
Drug Des Devel Ther. 2020 Oct 28;14:4547-4560
PubMed

Laurent A, Hirt-Burri N, Scaletta C, Michetti M, de Buys Roessingh AS, Raffoul W, Applegate LA
Holistic Approach of Swiss Fetal Progenitor Cell Banking: Optimizing Safe and Sustainable Substrates for Regenerative Medicine and Biotechnology.
Front Bioeng Biotechnol. 2020 Oct 23;8:557758
PubMed

Bhattacharya I, Ghayor C, Pérez Dominguez A, Weber FE
From Influenza Virus to Novel Corona Virus (SARS-CoV-2)-The Contribution of Obesity.
Front Endocrinol (Lausanne). 2020 Oct 6;11:556962
PubMed

Khera N, Ghayor C, Lindholm AK, Pavlova E, Atanassova N, Weber FE

N, N-Dimethylacetamide, an FDA approved excipient, acts post-meiotically to impair spermatogenesis and cause infertility in rats.
Chemosphere. 2020 Oct;256:127001
PubMed

Kadooka K, Anagnostakou V, Bozinov O, Kulcsár Z
Delayed mesencephalic venous infarction after endovascular treatment of a giant aneurysm of the posterior cerebral artery: Case report and anatomical review.
Interv Neuroradiol. 2020 Oct;26(5):593-597
PubMed

* Gantenbein B, Croft AS, Larraillet M
Mammalian Cell Viability Methods in 3D Scaffolds for Tissue Engineering.
Fluorescence Methods for Investigation of Living Cells and Microorganisms, Natalia Grigoryeva, IntechOpen.
2020 Sep 30

IntechOpen

* Bakirci E, Tschan K, May RD, Ahmad SS, Kleer B, Gantenbein B
The importance of plasmin for the healing of the anterior cruciate ligament.
Bone Joint Res. 2020 Sep 3;9(9):543-553
PubMed

** Tai YK, Ng C, Purnamawati K, Yap JLY, Yin JN, Wong C, Patel BK, Soong PL, Pelczar P, Fröhlich J, Beyer C, Fong CHH, Ramanan S, Casarosa M, Cerrato CP, Foo ZL, Pannir Selvan RM, Grishina E, Degirmenci U, Toh SJ, Richards PJ, Mirsaidi A, Wuertz-Kozak K, Chong SY, Ferguson SJ, Aguzzi A, Monici M, Sun L, Drum CL, Wang JW, Franco-Obregón A
Magnetic fields modulate metabolism and gut microbiome in correlation with Pgc-1α expression: Follow-up to an in vitro magnetic mitohormetic study.
FASEB J. 2020 Aug;34(8):11143-11167
PubMed

** Kling S, Hufschmid FS, Torres-Netto EA, Randleman JB, Willcox M, Zbinden R, Hafezi F
High Fluence Increases the Antibacterial Efficacy of PACK Cross-Linking.
Cornea. 2020 Aug;39(8):1020-1026
PubMed

* Cornaz F, Valet S, Meyer DC
Spectroscopic characterization of tissue and liquids during arthroscopic radio-frequency ablation.
Med Phys. 2020 Aug;47(8):3703-3709
PubMed

*/** Nytko KJ, Thumser-Henner P, Russo G, Weyland MS, Rohrer Bley C
Role of HSP70 in response to (thermo)radiotherapy: analysis of gene expression in canine osteosarcoma cells by RNA-seq
Sci Rep. 2020 Jul 29;10(1):12779
PubMed

** Hafezi F, Hafezi NL, Pajic B, Gilardoni F, Randleman JB, Gomes JAP, Kollros L, Hillen M, Torres-Netto EA
Assessment of the mechanical forces applied during eye rubbing.
BMC Ophthalmol. 2020 Jul 22;20(1):301
PubMed

* Filippo Buono M, von Boehmer L, Strang J, Hoerstrup SP, Emmert MY, Nugraha B
Human Cardiac Organoids for Modeling Genetic Cardiomyopathy.
Cells. 2020 Jul 20;9(7):1733
PubMed

** Weyland MS, Thumser-Henner P, Nytko KJ, Rohrer Bley C, Ulzega S, Petri-Fink A, Lattuada M, Füchslin RM, Scheidegger S
Holistic View on Cell Survival and DNA Damage: How Model-Based Data Analysis Supports Exploration of Dynamics in Biological Systems.
Comput Math Methods Med. 2020 Jul 6;2020:5972594
PubMed

Sadoughifar R, Goldust M, Abdshahzadeh H, Abrishamchi R, Rudnicka L, Jafferany M, Gupta M
Artificial intelligence in diagnosis and management of COVID-19 in dermatology.
Dermatol Ther. 2020 Jul;33(4):e13794
PubMed

Flück M, Fitze D, Ruoss S, Valdivieso P, von Rechenberg B, Bratus-Neuenschwander A, Opitz L, Hu J, Laczko E, Wieser K, Gerber C
Down-Regulation of Mitochondrial Metabolism after Tendon Release Primes Lipid Accumulation in Rotator Cuff Muscle.
Am J Pathol. 2020 Jul;190(7):1513-1529
PubMed

* Schmid B, Hausmann O, Hitzl W, Achermann Y, Wuertz-Kozak K
The Role of Cutibacterium acnes in Intervertebral Disc Inflammation.
Biomedicines. 2020 Jun 30;8(7):186
PubMed

Laurent A, Lin P, Scaletta C, Hirt-Burri N, Michetti M, de Buys Roessingh AS, Raffoul W, She BR, Applegate LA
Bringing Safe and Standardized Cell Therapies to Industrialized Processing for Burns and Wounds.
Front Bioeng Biotechnol. 2020 Jun 19;8:581
PubMed

Aslanides IM, Hafezi F, Chen S, Mukherjee H, Selimis V, Maragkos I, Lu N, Kymionis G
5-year efficacy of all surface laser ablation with cross-linking (ASLA-XTRA) for the treatment of myopia.
Eye Vis (Lond). 2020 Jun 11;7:31
PubMed

** Kling S, Torres-Netto EA, Spiru B, Sekundo W, Hafezi F
Quasi-Static Optical Coherence Elastography to Characterize Human Corneal Biomechanical Properties.
Invest Ophthalmol Vis Sci. 2020 Jun 3;61(6):29
PubMed

Schwarzenberg P, Darwiche S, Yoon RS, Dailey HL
Imaging Modalities to Assess Fracture Healing.
Curr Osteoporos Rep. 2020 Jun;18(3):169-179
PubMed

Wright B, Kronen PW, Lascelles D, Monteiro B, Murrell JC, Robertson S, Steagall PVM, Yamashita K
Ice therapy: cool, current and complicated.
J Small Anim Pract. 2020 May;61(5):267-271
PubMed

** McLuckie M, Robotti F, Sanchez-Macedo N, Enderlin D, Frese L, Cheng PF, Levesque MP, Egaña JT, Poulikakos D, Ferrari A, Lindenblatt N
Lipoconstruct surface topography grating size influences vascularization onset in the dorsal skinfold chamber model.
Acta Biomater. 2020 Apr 1;106:136-144
PubMed

** Knyazer B, Krakauer Y, Abu Tailakh M, Achiron A, Hecht I, Lifshitz T, Torres-Netto EA, Hafezi NL, Hafezi F
Accelerated Corneal Cross-linking as an Adjunct Therapy in the Management of Presumed Bacterial Keratitis: A Cohort Study.
J Refract Surg. 2020 Apr 1;36(4):258-264
PubMed

Voelter K, Tappeiner C, Riond B, Nuss K, Bruetsch D, Pot SA
Evaluation of D-dimer levels in aqueous humor of rabbit eyes with and without induced intraocular fibrin and fibrinolytic treatment
Vet Ophthalmol, 2020 Mar;23(2):212-218

PubMed

* May RD, Frauchiger DA, Albers CE, Hofstetter W, Gantenbein B
Exogenous Stimulation of Human Intervertebral Disc Cells in 3-Dimensional Alginate Bead Culture With BMP2 and L51P: Cytocompatibility and Effects on Cell Phenotype
Neurospine, 2020 Mar;17(1):77-87

PubMed

* Krupkova O, Greutert H, Boos N, Lemcke J, Liebscher T, Wuertz-Kozak K
Expression and activity of hyaluronidases HYAL-1, HYAL-2 and HYAL-3 in the human intervertebral disc
Eur Spine J, 2020 Mar;29(3):605-615

PubMed

Siegenthaler B, Ghayor C, Ruangsawasdi N, Weber FE
The Release of the Bromodomain Ligand N,N-Dimethylacetamide Adds Bioactivity to a Resorbable Guided Bone Regeneration Membrane in a Rabbit Calvarial Defect Model.
Materials (Basel). 2020 Jan 21;13(3):501
PubMed

** Torres-Netto EA, Spiru B, Kling S, Gilardoni F, Lazaridis A, Sekundo W, Hafezi F
Similar Biomechanical Cross-linking Effect After SMILE and PRK in Human Corneas in an Ex Vivo Model for Postoperative Ectasia.
J Refract Surg. 2020 Jan 1;28(1):49-54
PubMed

* Barreto G, Senturk B, Colombo L, Brück O, Neidenbach P, Salzmann G, Zenobi-Wong M, Rottmar M
Lumican is upregulated in osteoarthritis and contributes to TLR4-induced pro-inflammatory activation of cartilage degradation and macrophage polarization.
Osteoarthritis Cartilage. 2020 Jan;28(1):92-101
PubMed

Meier AF, Laimbacher AS
HSV-1 Amplicon Vectors as Genetic Vaccines.
Methods Mol Biol. 2020;2060:111-130
PubMed

Laurent A, Darwiche SE, Hirt-Burri N, Scaletta C, Michetti M, Laurent P, Raffoul W, de Buys Roessingh AS, Applegate LA
Banking Progenitor Cells for Hippiatric Regenerative Medicine: Optimized Establishment of Safe and Consistent Cell Sources for Standardized Veterinary Therapeutic Protocols.
Am J Biomed Sci Res. 2020;8(4)
Biomed

Borel N, Sauer-Durand AM, Hartel M, Kuratli J, Vaupel P, Scherr N, Pluschke G
wIRA: hyperthermia as a treatment option for intracellular bacteria, with special focus on Chlamydiae and Mycobacteria.
Int J Hyperthermia. 2020;37(1):373-383
PubMed